Please see below a list of publications arising from some of the scintigraphy studies we have conducted (2000 - 2010). We are able to provide re-prints of some of the articles, please contact us for futher information.

Blanchard, J., Cipolla, D., Liu, K., Morishige, R., Mudumba, S., Thipphawong, J., Taylor, G., Warren, S., Radhakrishnan, R., Van Vlasselaer, R., Visor , G. and Starko, K. Lung Deposition of Interferon Gamma-1b following Inhalation via AERx® System vs. Respirgard II™ Nebulizer Proc. ATS Annual Meeting (Abstract A373), Seattle (2003).

Boyd, B., Noymer; P., Liu K., Okikawa, J., Hasegawa D., Warren, S., Taylor G., Ferguson, E., Schuster J., Farr, S., and Gonda, I. - Effect of gender and device mouthpiece shape on bolus insulin aerosol delivery using the AERx pulmonary delivery system. Pharm. Res. 21, 1776-1782 (2004).

Boyd, B., Liu, K., Okikawa, J., Noymer, P., Hasegawa, D., Warren, S., Taylor, G., Ferguson, E., Farr, S., and Gonda, I. - The effect of different mouthpiece shapes on bolus aerosol delivery in males and females using the AERx® pulmonary delivery system. In Drug Delivery to the Lungs XI. 86-89 (2000).

Cipolla, D., Boyd, B., Evans, R., Warren, S.J, Taylor, G., and Farr S.J. - Bolus administration of high dose drugs: studies using the AERx® pulmonary delivery system to deliver INS365. Proc. Resp. Drug Delivery VII, 231-239 (2000).

Evans, R., Kaufman, B., Kellerman, D., Boyd, B., Farr, S., Taylor, G. and Warren S. Characterization of the in-vitro and in-vivo performance of two popular air-jet nebulizers. J. Allergy Clin. Immunol. 107S 829 (2001).

Evans, R., Johnson, F., Kaufman, B., Kellerman, D., Boyd, B., Cipolla, D., Farr, S., Taylor, G., Warren, S. and Ferguson, E. High lung doses of a novel therapeutic agent achieved using a novel delivery system. In Drug Delivery to the Lungs XI. 78-81 (2000).

Evans, R., Johnson, F., Kaufman, B., Kellerman, D., Boyd, B., Cipolla, D., Farr, S., Taylor, G. and Warren, S. – Aerosolized INS365 for COPD: Enhanced deposition and clearance using the AERx delivery system. Am. J. Respir. Crit. Care Medicine 161: A815 (2000).

Farr, S., Warren, S., Lloyd, P., Okikawa, J., Schuster, J., Rowe, A., Rubsamen, R. and Taylor G. Comparison of in vitro and in vivo efficiencies of a novel unit-dose liquid aerosol generator and a pressurized metered dose inhaler. Int. J. Pharmaceut. 198, 63-70 (2000).

Hampson F, Jolliffe, I, Bakhtyari A, Taylor G, Sykes J, Johnstone L, Dettmar P. Alginate-antacid combinations: raft formation and gastric retention studies. Drug Dev Ind Pharm. 36(5):614-23 (2010).

Jones, R., Evans, R., Warren S. and Taylor, G. - Development of a fluticasone suspension pMDI formulation using a second particulate system. In Respiratory Drug Delivery IX, 3, 401-404 (2004).

Jones, R., Evans, R., Warren, S., and Taylor, G. - Development of a novel suspension MDI formulation using a low energy dispersion system. Respiratory Drug Delivery VIII, 799 – 802 (2002).

Nikander K, Prince I, Coughlin S, Warren S, Taylor G. Mode of breathing – tidal or slow and deep – through the I-neb Adaptive Aerosol Delivery (AAD) system affects lung deposition of 99mTc-DTPA. J. Aerosol Medicine Pulm. Drug Del. 23(S1):S37-S43 (2010).

Nikander, K., Prince, I., Coughlin, S., Warren, S. and Taylor, G. - Lung deposition of 99mTc-DTPA delivered with the I-neb® Adaptive Aerosol Delivery (AAD®) System. J. Aerosol Medicine 20, 192-193 (2007).

Scheuch G, Bennett W, Borgstrom L, Clark A, Dalby R, Dolovich M, Fleming J, Gehr P, Gonda I, O'Callaghan C, Taylor G, Newman S. Deposition, Imaging, and Clearance: What Remains to be Done? J. Aerosol Medicine Pulm. Drug Del. 23(S2): S39-S57 (2010).

Shrewsbury S, Cook R, Taylor G, Edwards C, Ramadan N. Safety and Pharmacokinetics of Dihydroergotamine Mesylate Administered via a Novel (Tempo(TM)) Inhaler. Headache 48: 355-367 (2008).

Taylor G. The Highs and Lows of Pharmacokinetics in Determining the Equivalence of Inhaled Medicinal Products. In Proceedings of Drug Delivery to the Lungs 21: 9-14 (2010).

Taylor, G., Tran C., Warren, S., Thomas I. and Marchetti, G. - The Kemp HFA pMDI valve for delivery of novel budesonide/formoterol fumarate combination formulations. Respiratory Drug Delivery XI, 983 – 986 (2008).

Taylor, G., Thomas, I., Warren, S., Kellerman, D. and Momose, D. - Gamma scintigraphic evaluation of INS365 deposition following JetHaler DPI administration. J. Aerosol Medicine 20, 193 (2007).

Taylor, G., Warren, S., McRae, D., Venitz, J. - Human deposition and exposure studies with propylene glycol aerosols produced using the CAG technology platform. In Respiratory Drug Delivery X, 1, 183-190 (2006).

Tran, C. Bray, H., Evans, R. and Taylor, G. - The effects of excipient surface interactions on aerosol performance of pressurised meter dose inhalers. J. Pharm. Pharmacol. 57, S21 (2005).

Tran, C., Evans, R. and Taylor, G. – Analysis of novel pressurised metered dose inhaler (pMDI) formoterol fumarate formulations. In Proceedings of Drug Delivery to the Lungs XVI, Aerosol Society, 253-256 (2005).

Tran, C., Harries, A., Chi, P., Evans, R. and Taylor, G. - Amino acids as excipients in pressurised metered dose inhaler formulations. In Proceedings of Drug Delivery to the Lungs XV, Aerosol Society, 137-140 (2004).

Tran, C., Harries, A., Chi, P., Evans, R. and Taylor, G. – Alternative amino acids as potential secondary particulates in pressurised metered dose inhaler formulations. Eur. J Pharm. Sci. 23S, S63 (2004).

Warren, S. and Taylor, G. - Quality control aspects of pharmaceutical gamma scintigraphy studies. Eur. Pharm. Contractor, 2004, 1, 76-83 (2004).

Warren, S. and Taylor, G. Morphometric measures for tissue attenuation corrections in pharmaceutical scintigraphy. AAPS Pharm Sci 5 (4) Abstract M1079 (2003).

Warren, S., Taylor, G., Smith, J., Buck, H. and Parry-Billings, M. - Gamma scintigraphic evaluation of a novel budesonide dry powder inhaler using a validated radiolabeling technique. J. Aerosol Medicine 15, 15-25 (2002).

Warren, S., and Taylor, G. Scintigraphic Analysis in the Clinical Research of Pharmaceuticals. European Pharmaceutical Contractor, May, pp.54 – 61 (2001).

Weers J, Metzheiser B, Taylor G, Warren S, Meers P, Perkins WR. A gamma scintigraphy study to investigate lung deposition and clearance of inhaled amikacin-loaded liposomes in healthy male volunteers. J. Aerosol Medicine Pulm. Drug Del. 22: 131-138 (2009).

Weers, J, Metzheiser, B, Perkins, W, Meers, P., Nicholson, S., Taylor, G., Warren, S., Pilkiewicz, F. A Pulmonary Sustained Release Formulation of Amikacin (SLIT™ Amikacin) for Pseudomonas aeruginosa Infections in CF Patients.Proc. ATS Annual Meeting, San Diego (2005).